Self-suppression from metabolin with a precursor in pathology crystallization of gout?
CrystEngComm Pub Date: 2019-06-04 DOI: 10.1039/C9CE00214F
Abstract
Hyperuricemia is typically defined as occurring above the saturation point of monosodium urate monohydrate (MSUM), which occurs at serum urate levels >6.8 mg dL?1. Xanthine(X), a precursor molecule of uric acid, was found to inhibit the growth of MSUM crystals through incorporating into the surface of bulk crystal of MSUM. This approach can provide us with a new perspective that will help our understanding of the heterogeneity of gout in hyperuricemics and the processes of crystal formation and growth of MSUM.
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Journal Name：CrystEngComm
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CAS no.: 89640-58-4
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