Unprecedented synergistic effects between weak Lewis and Br?nsted acids in Prins cyclization?

Chemical Communications Pub Date: 2012-07-24 DOI: 10.1039/C2CC35052A

Abstract

Novel synergistic effects between Lewis and Br?nsted acids in Prins cyclization are reported. Non-reactive Lewis acids and non-reactive Br?nsted acids, which failed to perform Prins cyclization when used alone, have shown remarkable synergistic effects when used in combination to perform the reaction successfully.

Graphical abstract: Unprecedented synergistic effects between weak Lewis and Br?nsted acids in Prins cyclization
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