Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction?
RSC Advances Pub Date: 2014-07-29 DOI: 10.1039/C4RA07088G
Abstract
An efficient method of palladium-catalyzed direct arylation has been developed for the selective functionalization of the C6 position of 2,4-diarylpyrrolo[2,3-d]pyrimidines. Under optimal conditions, various aryl bromides successfully provided a wide range of 6-arylpyrrolo[2,3-d]pyrimidines.
![Graphical abstract: Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C–H arylation reaction](http://scimg.chem960.com/usr/1/C4RA07088G.jpg)
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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