Access to 2,5-disubstituted tetrahydrofurans from Grignard reagents and hemiacetal derivatives

Chemical Communications Pub Date: 2001-12-20 DOI: 10.1039/B109930M

Abstract

The first diastereoselective addition of Grignard reagents onto cyclic oxocarbenium ions, obtained from glycosyl acetates, to afford 2,5-disubstituted tetrahydrofurans, is reported.

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