Tuning the reactivity of Au-complexes in an Au(i)/chiral Br?nsted acid cooperative catalytic system: an approach to optically active fused 1,2-dihydroisoquinolines?
Chemical Communications Pub Date: 2012-01-30 DOI: 10.1039/C2CC17450B
Abstract
An enantioselective cooperative catalysis protocol, utilizing achiral Au(I) complexes and chiral Br?nsted acids, has been developed for the synthesis of optically pure fused 1,2-dihydroisoquinolines starting from 2-alkynylbenzaldehydes and 2-aminobenzamides.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4