Reversible chemoselective transetherification of vinylogous esters using Fe-catalyst under additive free conditions?
Organic & Biomolecular Chemistry Pub Date: 2019-02-20 DOI: 10.1039/C9OB00307J
Abstract
An additive/Br?nsted acid/base free, highly efficient and chemoselective transetherification of electron deficient vinylogous esters and water mediated de-alkylation using an earth-abundant Fe-catalyst under very mild reaction conditions is described. This reaction is highly selective to primary alcohols over secondary alcohols, has good functional group tolerance, is scalable to gram scale and a purification free sequential transetherification in a continuous flow mode is demonstrated.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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