Synthesis of imidazolidin-2-one-4-carboxylate and of (tetrahydro)pyrimidin-2-one-5-carboxylatevia an efficient modification of the Hofmann rearrangement?
Organic & Biomolecular Chemistry Pub Date: 2008-04-07 DOI: 10.1039/B801909F
Abstract
A mild and efficient methodology for the rearrangement of protected asparagine and protected glutamine is reported; good results are obtained with a wide selection of protecting groups.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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