Synthesis of cinnolines via Rh(iii)-catalysed dehydrogenative C–H/N–H functionalization: aggregation induced emission and cell imaging?
Organic & Biomolecular Chemistry Pub Date: 2016-01-05 DOI: 10.1039/C5OB02045J
Abstract
Rhodium catalysed dehydrogenative C–H/N–H functionalization was developed to construct phthalazino[2,3-a]-/indazolo[1,2-a]cinnolines by reacting N-phenyl phthalazine/indazole with alkynes. The synthesized compounds exhibit prominent fluorescence properties in solid and aggregation states. Their application in cell imaging was investigated using various cancer cell lines.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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