Regioselective synthesis and theoretical studies of an anti-neoplastic fluoro-substituted dispiro-oxindole?
RSC Advances Pub Date: 2015-01-13 DOI: 10.1039/C4RA13433H
Abstract
Single crystal X-ray studies of regioselectively synthesized fluoro-substituted dispiro-oxindole 9 revealed that the structure belongs to the monoclinic space group P21/n with four molecules in the unit cell. The structure was also investigated by AM1, PM3, and DFT studies. Compound 9 exhibits high potency against the HeLa cell line.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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