A viable strategy for screening the effects of glycan heterogeneity on target organ adhesion and biodistribution in live mice?
Chemical Communications Pub Date: 2018-06-25 DOI: 10.1039/C8CC01544A
Abstract
This work represents the first broad study of testing diverse heterogenous glycoconjugates (7 different glycoalbumins) for their differential in vivo binding (11 different cancer cell types) in both cell- and animal-based studies. As a result, various changes in biodistribution, excretion, and even tumor adhesion were observed.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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