A simple regiospecific strategy for labelling hydrogen atoms in α-amino acids

Chemical Communications Pub Date: 2000-11-22 DOI: 10.1039/B007662G

Abstract

Simple methods for the regioselective introduction of deuterium labels at the α- and β-carbon atoms of leucine using a Co(III) imino acid complex are described which have a general applicability to the synthesis of a range of labelled amino acids.

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