A simple photo-affinity labeling protocol
Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A809507H
Abstract
After photo-crosslinking and proteolysis of a photoaffinity labeled ligand to its receptor, the ester group incorporated in the ligand is cleaved by an amine with specific functionality, which displaces the bulk of the ligand from the peptide fragments, and facilitates subsequent tandem mass spectrometric sequencing.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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