Reactivity of adrenaline toward alkoxyl radicals and carbonyl triplet states

Organic & Biomolecular Chemistry Pub Date: 2008-10-31 DOI: 10.1039/B810765C

Abstract

The reactivities of adrenaline toward hydrogen abstraction by the tert-butoxyl radical and the excited triplet state of benzophenone have been examined in solution using laser flash photolysis techniques. The rate constants obtained in acetonitrile-rich solvents are 13 and 1.5 × 108 M?1 s?1 for benzophenone triplet and the tert-butoxyl radical, respectively. Adrenaline is a better hydrogen donor than phenol, but not as efficient as α-tocopherol.

Graphical abstract: Reactivity of adrenaline toward alkoxyl radicals and carbonyl triplet states
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