The merger of natural product synthesis and medicinal chemistry: on the chemistry and chemical biology of epothilones

Organic & Biomolecular Chemistry Pub Date: 2004-07-14 DOI: 10.1039/B405839A

Abstract

Based on epothilones as powerful natural product leads several promising new anticancer agents have emerged through concerted efforts in chemistry and biology.

Graphical abstract: The merger of natural product synthesis and medicinal chemistry: on the chemistry and chemical biology of epothilones
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