SelectfluorTM F-TEDA-BF4 mediated and solvent directed iodination of aryl alkyl ketones using elemental iodine?
Chemical Communications Pub Date: 2002-02-08 DOI: 10.1039/B200240J
Abstract
Reactions of aryl alkyl ketones with methanol solution of elemental iodine and 1-fluoro-4-chloromethyl-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) (Selectfluor? F-TEDA-BF4) result in the formation of corresponding α-iodo ketones, while switch over of the regioselectivity can be directed by using acetonitrile as the solvent and selective iodination of the aromatic site of target molecules is thus achieved.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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