Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Chemical Communications Pub Date: 2005-02-15 DOI: 10.1039/B418666D

Abstract

Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two “matched” elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.

Graphical abstract: Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones
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