Synthesis of oxazepin-quinoxaline bis-heterocyclic scaffolds via an efficient three component synthetic protocol?
RSC Advances Pub Date: 2014-09-15 DOI: 10.1039/C4RA08486A
Abstract
An efficient protocol has been developed to access a series of novel highly complex bis-heterocyclic oxazepin-quinoxaline derivatives. The new bifunctional compounds were synthesized via a one-pot three component reaction between 2-(2-formylphenoxy)acetic acid, an amine and 6-hydroxybenzo[f]quinoxaline-2,3-dicarbonitrile in toluene under reflux conditions without using any catalyst in good to excellent yields.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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