Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization?

Organic & Biomolecular Chemistry Pub Date: 2011-03-22 DOI: 10.1039/C1OB05258F

Abstract

An efficient methodology for the synthesis of highly functionalized ellipticinium and ellipticine derivatives starting from the corresponding 2-bromocarbazoles via an AgOTf or CuI catalyzed electrophilic cyclization of 2-alkynyl-3-carbazolylaldimines is reported.

Graphical abstract: Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization
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