2,4-Diamino-6,7-dimethylpteridine as a fluorescent ligand for binding and sensing an orphan cytosine in RNA duplexes?
Chemical Communications Pub Date: 2013-09-05 DOI: 10.1039/C3CC46085A
Abstract
We report on a new fluorescent ligand, 2,4-diamino-6,7-dimethylpteridine, that can strongly and selectively bind to an orphan cytosine opposite an abasic site in RNA duplexes. We describe a significant effect of the substituents attached to the pteridine ring on the binding behavior in comparison with a structurally-similar pteridine derivative.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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