Rhodium-catalyzed addition of sulfonyl hydrazides to allenes: regioselective synthesis of branched allylic sulfones?

Chemical Communications Pub Date: 2017-04-07 DOI: 10.1039/C7CC02375H

Abstract

A rhodium-catalyzed regioselective addition of sulfonyl hydrazides to allenes is reported. With Rh(I)/DPEphos/benzoic acid as the catalyst system, branched allylic sulfones can be obtained, in good to excellent yields and regioselectivities.

Graphical abstract: Rhodium-catalyzed addition of sulfonyl hydrazides to allenes: regioselective synthesis of branched allylic sulfones
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