Rhodium(iii)-catalyzed directed C–H benzylation and allylation of indoles with organosilicon reagents?
Organic Chemistry Frontiers Pub Date: 2016-11-29 DOI: 10.1039/C6QO00589F
Abstract
Rhodium(III)-catalyzed C2-benzylation and allylation of indoles with organosilicon reagents via chelation-assisted C–H activation has been developed. This protocol demonstrates a board substrate scope, tolerates a broad range of synthetically useful functional groups, and enables a straightforward route to C2-benzyl- and allylindole derivatives.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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