7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off–on probe for highly sensitive and selective detection of nitroreductase?

Chemical Communications Pub Date: 2013-05-14 DOI: 10.1039/C3CC42610F

Abstract

A new spectroscopic off–on probe, 7-((5-nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one, is developed and applied to real-time detection of nitroreductase produced by Escherichia coli.

Graphical abstract: 7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off–on probe for highly sensitive and selective detection of nitroreductase
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