Studies on the synthesis of a sugar triazole based ligand for protein and DNA binding?

RSC Advances Pub Date: 2014-07-29 DOI: 10.1039/C4RA04084H

Abstract

Bis-triazole derivatives accomplished by [3 + 2] cycloaddition methodology were well characterized. Interaction of bis-triazoles with BSA and CT-DNA had good correlation with experimental and docking studies. The compounds showed moderate to excellent antibacterial activity.

Graphical abstract: Studies on the synthesis of a sugar triazole based ligand for protein and DNA binding
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