Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons?

Organic & Biomolecular Chemistry Pub Date: 2011-04-21 DOI: 10.1039/C0OB01107J

Abstract

Convergent synthetic pathways were devised for efficient synthesis of a series of uniformly 13C labeled polycyclic aromatic hydrocarbons de novo from U-13C-benzene and other simple commercially-available 13C-starting compounds. All target products were obtained in excellent yields, including the alternant PAH U-13C-naphthalene, U-13C-phenanthrene, U-13C-anthracene, U-13C-benz[a]anthracene, U-13C-pyrene and the nonalternant PAH U-13C-fluoranthene.

Graphical abstract: Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons
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