Simple and expeditious pinacol coupling of non usual α,β-unsaturated carbonyl compounds in water??

RSC Advances Pub Date: 2015-05-15 DOI: 10.1039/C5RA03870G

Abstract

Using zinc (0) in a 5% v AcOH aqueous solution allowed the efficient pinacol coupling of aliphatic or aromatic unusual, α,β-unsaturated carbonyl compounds such as citral A in good to excellent yields (56–99%). It can also be successfully applied to acetophenone.

Graphical abstract: Simple and expeditious pinacol coupling of non usual α,β-unsaturated carbonyl compounds in water
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