Polymer nanoreactors shown to produce and release antibiotics locally?

Chemical Communications Pub Date: 2012-10-05 DOI: 10.1039/C2CC36345C

Abstract

We designed and prepared nanoreactors based on a poly(2-methyloxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyloxazoline (PMOXA-b-PDMS-b-PMOXA) amphiphilic triblock copolymer encapsulating the enzyme penicillin acylase for local and controlled production of antibiotics.

Graphical abstract: Polymer nanoreactors shown to produce and release antibiotics locally
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