Stereoselective synthesis and applications of spirocyclic oxindoles
Organic Chemistry Frontiers Pub Date: 2021-01-06 DOI: 10.1039/D0QO01085E
Abstract
The development of novel synthetic strategies to form new chemical entities in a stereoselective manner is an ongoing significant objective in organic and medicinal chemistry. This review analyses the development of new stereoselective approaches to spirocyclic oxindoles with spiro-3- to 8-membered rings. It highlights the importance of these structures for applications in medicinal chemistry, as intermediates or final products in total synthesis and as model compounds for the development of enantioselective catalytic methodologies.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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