Synthesis and applications of 1-iodo-4-MgCl-1,3-dienes and 1-iodovinyl phenylmagnesium chlorides?
Organic Chemistry Frontiers Pub Date: 2014-08-08 DOI: 10.1039/C4QO00191E
Abstract
Selective I/Mg exchange reactions of 1,4-diiodo-1,3-dienes and o-iodo-2-(2-iodovinyl)benzenes were achieved viaiPrMgCl·LiCl. Various 1-iodo-4-MgCl-1,3-dienes and 1-iodovinyl phenylmagnesium chlorides were thus efficiently generated and synthetically applied to afford new C–C bonds via reactions of the alkenyl or aryl C–MgCl bonds with different electrophiles. Useful conjugated compounds including polysubstituted benzenes, naphthalenes and phosphine compounds could be synthesized readily via further applications of the remaining alkenyl C–I bonds and subsequent cyclization reactions.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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