Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system?

Organic & Biomolecular Chemistry Pub Date: 2009-11-26 DOI: 10.1039/B915677A

Abstract

A study of the effect of substrate structure on a Claisen-aza-Cope reaction is presented including a rationalisation of the reaction outcome using DFT calculations. An asymmetric version of the reaction is also described that is of relevance to a proposed approach to the communesin family of natural products.

Graphical abstract: Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system
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