Palladium-catalyzed ligand-free and efficient Suzuki–Miyaura reaction of heteroaryl halides with MIDA boronates in water?
RSC Advances Pub Date: 2015-06-15 DOI: 10.1039/C5RA10001A
Abstract
A simple and environment-friendly protocol for the palladium-catalyzed ligand-free Suzuki–Miyaura reaction of heteroaryl halides with N-methyliminodiacetic acid (MIDA) boronates is developed. The reaction is performed in water as the sole medium and allows the preparation of a variety of heterobiaryls in excellent yields.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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