Palladium(ii)-catalyzed intermolecular oxidative C-3 alkenylations of imidazo[1,2-a]pyridines by substrate-contolled regioselective C–H functionalization?
RSC Advances Pub Date: 2014-09-30 DOI: 10.1039/C4RA09669J
Abstract
An efficient and highly regioselective palladium(II)-catalyzed oxidative C-3 alkenylation of imidazo[1,2-a]pyridines with acrylate, acrylonitrile, or vinylarenes has been developed by using oxygen as an oxidant. Substrates such as acrylate and acrylonitrile tended to form β-product, while vinylarenes tended to form the sole α-products.
![Graphical abstract: Palladium(ii)-catalyzed intermolecular oxidative C-3 alkenylations of imidazo[1,2-a]pyridines by substrate-contolled regioselective C–H functionalization](http://scimg.chem960.com/usr/1/C4RA09669J.jpg)
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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