Palladacycle-catalyzed Suzuki–Miyaura reaction of aryl/heteroaryl halides with MIDA boronates in EtOH/H2O or H2O?

RSC Advances Pub Date: 2014-08-07 DOI: 10.1039/C4RA07486F

Abstract

With good to excellent yields, a series of mono- or diheteroaryl compounds were synthesized via the palladacycle-catalyzed Suzuki–Miyaura reaction of various N-methyliminodiacetic acid (MIDA) boronates with aryl/heteroaryl halides in EtOH/H2O or H2O.

Graphical abstract: Palladacycle-catalyzed Suzuki–Miyaura reaction of aryl/heteroaryl halides with MIDA boronates in EtOH/H2O or H2O
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