Palladium-catalyzed regioselective allylation of five-membered heteroarenes with allyltributylstannane?

Chemical Communications Pub Date: 2015-01-27 DOI: 10.1039/C4CC10373D

Abstract

Palladium-catalyzed allylation reactions of 2-(chloromethyl)thiophenes, 2-(chloromethyl)furans, and N-protected 2-(chloromethyl)-1H-pyrroles with allyltributylstannane were described in this study. This type of allylation reaction regioselectively occurred on the heteroarene rings to produce allylated dearomatization products or allylated heteroarenes with satisfactory yields.

Graphical abstract: Palladium-catalyzed regioselective allylation of five-membered heteroarenes with allyltributylstannane
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