A red-emitting fluorescent probe for hydrogen sulfide in living cells with a large Stokes shift?

Organic & Biomolecular Chemistry Pub Date: 2018-01-17 DOI: 10.1039/C7OB02641B

Abstract

A red-emitting fluorescent probe was developed for the sensitive and selective detection of H2S. Upon treatment with H2S, this probe exhibited a remarkable fluorescence enhancement (10 fold) with a large Stokes shift (125 nm). The detection limit of this probe was as low as 5.7 nM based on S/N = 3. The application of this probe in the detection of intracellular H2S in living cells is successfully demonstrated.

Graphical abstract: A red-emitting fluorescent probe for hydrogen sulfide in living cells with a large Stokes shift
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