Palladium-catalyzed synthesis of benzoxazoles by the cleavage reaction of carbon–carbon triple bonds with o-aminophenol?

Green Chemistry Pub Date: 2014-01-17 DOI: 10.1039/C3GC42499E

Abstract

A novel and mild procedure for efficient synthesis of benzoxazoles by the cleavage reaction of carbon–carbon triple bonds with o-aminophenol in the presence of a catalytic amount of palladium chloride has been successfully developed, which provides rapid and efficient access to benzoxazoles.

Graphical abstract: Palladium-catalyzed synthesis of benzoxazoles by the cleavage reaction of carbon–carbon triple bonds with o-aminophenol
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