A serendipitous phosphonocarboxylate complex of boron: when vessel becomes reagent?

Chemical Communications Pub Date: 2011-05-09 DOI: 10.1039/C1CC10876J

Abstract

Under certain conditions, the phosphonocarboxylate analogue (3) of the bisphosphonate drug minodronate (4) in contact with borosilicate glassware reversibly forms an isolable dimer complex of boron, as revealed by the X-ray crystallographic structure of the (R,R/S,S) complex and supported by NMR and HRMS data.

Graphical abstract: A serendipitous phosphonocarboxylate complex of boron: when vessel becomes reagent
Recommended Literature