Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units?

Organic & Biomolecular Chemistry Pub Date: 2014-06-30 DOI: 10.1039/C4OB00829D

Abstract

Diketopiperazine (DKP) units are found in many bioactive small molecules. Here we report facile chemistry for incorporating diverse DKP units within peptoid and peptoid-like libraries made by solid-phase split and pool synthesis.

Graphical abstract: Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units
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