Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines?
Chemical Communications Pub Date: 2019-09-14 DOI: 10.1039/C9CC06339K
Abstract
Herein, we report the first example of synthesis of N-substituted lactams via an acceptorless dehydrogenative coupling of diols with primary amines in one step, which was enabled by combining Ru3(CO)12 with a hybrid N-heterocyclic carbene–phosphine–phosphine ligand as the catalyst.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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