A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C–S cyclisation followed by Ugi type 3CC cascade?
RSC Advances Pub Date: 2015-04-02 DOI: 10.1039/C5RA04175A
Abstract
A two-step diversity oriented synthetic protocol to a novel class of dihydrodibenzo[b,f][1,4]thiazepine-11-carboxamides has been developed. The first step ensures the synthesis of dibenzothiazepine via copper-mediated condition followed by Ugi–Joullié reaction of the resultant cyclic imine in the second step.
![Graphical abstract: A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C–S cyclisation followed by Ugi type 3CC cascade](http://scimg.chem960.com/usr/1/C5RA04175A.jpg)
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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