One-pot synthesis of 4-methylisoquinolines via a sequential Pd-catalyzed Heck reaction and intramolecular cyclization?
Organic & Biomolecular Chemistry Pub Date: 2013-09-13 DOI: 10.1039/C3OB41680A
Abstract
An efficient, one-pot synthesis of 4-methylisoquinolines via a cascade Pd-catalyzed Heck reaction, intramolecular cyclization and isomerization has been developed. This reaction has a wide range of substrates with various functional groups, and the corresponding products have been obtained in good yields.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4