Revealing the nature of thio-click reactions on the solid phase?

Chemical Communications Pub Date: 2011-03-21 DOI: 10.1039/C0CC05340F

Abstract

Thiol- and yne-functionalized beads were manufactured in a simple microfluidic setup. While CuAAC and thiol–yne reactions were performed on yne-functionalized beads, 9 different thiol–X reactions were compared, in terms of kinetics and conversion, on thiol-functionalized beads.

Graphical abstract: Revealing the nature of thio-click reactions on the solid phase
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