Regioselective Ir(iii)-catalyzed C–H alkynylation directed by 7-azaindoles?

Organic & Biomolecular Chemistry Pub Date: 2016-02-09 DOI: 10.1039/C6OB00179C

Abstract

Herein we report a novel iridium(III)-catalyzed ortho-mono-alkynylation of 7-azaindoles under mild conditions. This approach provides a general and straightforward access to form novel 7-azaindole derivatives with ample substrate scope and broad group tolerance.

Graphical abstract: Regioselective Ir(iii)-catalyzed C–H alkynylation directed by 7-azaindoles
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