Recent progress of C-glycosylation methods in the total synthesis of natural products and pharmaceuticals

Organic & Biomolecular Chemistry Pub Date: 2018-02-21 DOI: 10.1039/C8OB00032H

Abstract

Chemical C-glycosylation has been well developed to improve stereoselectivity in recent years. Due to its high efficiency to build C-glycosides or O-cyclic compounds, C-glycosylation has found widespread use in the synthesis of biologically active molecules. This review highlights the C-glycosylation methods that have been practised in the total synthesis of natural products and pharmaceuticals in the past decade.

Graphical abstract: Recent progress of C-glycosylation methods in the total synthesis of natural products and pharmaceuticals
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