Novel asymmetrically functionalized bis-dipicolylamine metal complexes: peripheral decoration of a potent anion recognition scaffold?

Organic & Biomolecular Chemistry Pub Date: 2009-10-12 DOI: 10.1039/B917692F

Abstract

We report the design and synthesis of a novel class of asymmetrically functionalized, ditopic bis-dipicolylamine (BDPA) ligands. A key feature of this research involved the controlled, sequential functional group decoration of a potent molecular recognition scaffold. Calorimetric screening identified a BDPA analogue as a highly potent (Ka~ 106 M?1) and selective sensor for inorganic phosphate.

Graphical abstract: Novel asymmetrically functionalized bis-dipicolylamine metal complexes: peripheral decoration of a potent anion recognition scaffold
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