Palladium-catalyzed unsymmetrical aryl couplings in sequence leading to o-teraryls: dramatic olefin effect on selectivity?

Chemical Communications Pub Date: 2010-05-11 DOI: 10.1039/C000526F

Abstract

Selectively substituted o-teraryls are obtained by palladium/norbornene-catalyzed reaction of aryl iodides, aryl bromides and aryl boronic acids in ordered sequence; high selectivity is attained thanks to the addition of diethyl maleate acting as palladium ligand.

Graphical abstract: Palladium-catalyzed unsymmetrical aryl couplings in sequence leading to o-teraryls: dramatic olefin effect on selectivity
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