4-(Dimethylamino)pyridine-catalysed iodolactonisation of γ,δ-unsaturated carboxylic acids?
Organic & Biomolecular Chemistry Pub Date: 2015-05-13 DOI: 10.1039/C5OB00806A
Abstract
4-(Dimethylamino)pyridine functioned as an excellent catalyst for iodolactonisation reactions of γ,δ-unsaturated carboxylic acids, affording γ-lactones, δ-lactones, or both under neutral conditions at room temperature. The effects of substrate structures on the iodolactonisation were investigated, and a catalytic mechanism is proposed.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4