Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis
Natural Product Reports Pub Date: 2018-04-13 DOI: 10.1039/C8NP00004B
Abstract
Covering: up to the end of 2017
The roles played by Rieske non-heme iron-dependent oxygenases in natural product biosynthesis are reviewed, with particular focus on experimentally characterised examples. Enzymes belonging to this class are known to catalyse a range of transformations, including oxidative carbocyclisation, N-oxygenation, C-hydroxylation and C–C desaturation. Examples of such enzymes that have yet to be experimentally investigated are also briefly described and their likely functions are discussed.
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Journal Name:Natural Product Reports
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CAS no.: 89640-58-4