Rapid formal hydrolysis of peptide-αthioesters?
Chemical Communications Pub Date: 2012-11-29 DOI: 10.1039/C2CC38229F
Abstract
In the presence of 2-mercaptoethanol peptide-αthioesters undergo smooth conversion to their corresponding peptide-αcarboxylates. This general and operationally simple reaction extends the utility of a promising new strategy for cleaving resin-bound Boc/
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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