Nickel-catalyzed decarbonylation of N-acylated N-heteroarenes?
Chemical Science Pub Date: 2019-05-29 DOI: 10.1039/C9SC02035G
Abstract
Nickel-catalyzed decarbonylation of N-acylated N-heteroarenes is developed. This method can be used to produce a variety of N-aryl heteroarenes, including pyrroles, indoles, carbazoles and phenoxazines, using benzoic acid derivatives as arylating reagents. Arylnickelamide intermediates that are relevant to the catalytic reaction were characterized by X-ray crystallography. When N-acylated benzimidazoles are used as substrates, decarbonylation accompanied 1,2-migration to form 2-arylated benzimidazoles.
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Journal Name：Chemical Science
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CAS no.: 89640-58-4
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