Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria?
Chemical Communications Pub Date: 2020-02-26 DOI: 10.1039/D0CC00155D
Abstract
Here we report the synthesis of a novel methylene blue-polymyxin conjugate and demonstrate its light-mediated killing of Gram-negative bacteria on skin models of infection demonstrating a 108 decrease in bacterial colony-forming units.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4